Laser tweezers in cell biology

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laser tweezers in cell biology

Methods in Cell Biology, Volume 55: Laser Tweezers in Cell Biology by Michael P. Sheetz

Volume 55 in Methods in Cell Biology is a concise laboratory book that emphasizes the methods and technologies needed to use single polarized laser light source that functions simultaneously as an optical trap and a dual-beam interferometer.
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* Provides a practical laboratory guide for methods and technologies used with laser tweezers
* Includes comprehensive and easy-to-follow protocols
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Published 01.07.2019

Optical tweezers: basics and applications

The trapping is stable only if the force of the laser light scattering from Optical tweezers have also been used to study living biological cells.
Michael P. Sheetz

Figure 4: Optical tweezers to study single motor proteins.

Thank you for visiting nature. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser or turn off compatibility mode in Internet Explorer. In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript. Optical tweezers or optical traps are devices that use a laser to trap a nanometre-to-micrometre-sized dielectric object in place.

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State-of-the art optical tweezers system

It enables the most comfortable manipulation of up to 20 single and living cells, microorganisms and microscopic particles. The tweezer has been working reliably, with excellent manipulation power and flexibility on various devices, from simply glass slides to microelectrodes on silicon. The MMI service was also professional, fast and considerate. The MMI CellManipulator optical tweezers system is based on the mechanical forces arising from a strongly focused laser beam. It enables comfortable, ultra-precise and contact-free manipulation of microscopic particles, single or living cells, or subcellular organisms and the measurement of intracellular activities.

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    With accuracy down to single piconewtons 10 12 N , optical traps measure forces exerted on microscopic objects without mechanically touching them.

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